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Efficacy of High-Dose Baclofen for Alcohol Use Disorder and Comorbid Bulimia: A Case Report.

Abstract
High-dose baclofen is a promising treatment for alcohol use disorder, with a specific action on craving. A more general action on craving in other addictive disorders has been suggested based on the hypothesis of a common neurobiological pathway in addictions. We report the case of a woman with both alcohol use disorder and bulimia nervosa. There was a positive response to high-dose baclofen on alcohol craving, but no response on food craving. The case illustrates that craving could be differentially responsive to anti-craving drugs.
AuthorsSébastien Weibel, Laurence Lalanne, Myriam Riegert, Gilles Bertschy
JournalJournal of dual diagnosis (J Dual Diagn) Vol. 11 Issue 3-4 Pg. 203-4 ( 2015) ISSN: 1550-4271 [Electronic] United States
PMID26457456 (Publication Type: Case Reports, Letter)
Chemical References
  • Baclofen
Topics
  • Adult
  • Alcoholism (complications, drug therapy)
  • Baclofen (therapeutic use)
  • Bulimia Nervosa (complications, drug therapy)
  • Craving
  • Diagnosis, Dual (Psychiatry)
  • Female
  • Humans
  • Treatment Outcome

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