| Abstract |
A mutation in the WDR4 gene, coding for a tRNA-modifying enzyme, leads to reduced levels of guanosine methylation in tRNA in patients with primordial dwarfism. |
| Authors | Liudmila Filonava, Adrian Gabriel Torres, Lluis Ribas de Pouplana |
| Journal | Genome biology
(Genome Biol)
Vol. 16
Pg. 216
(Oct 01 2015)
ISSN: 1474-760X [Electronic] England |
| PMID | 26429597
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
| Chemical References |
|
| Topics |
- Dwarfism, Pituitary
(genetics, pathology)
- Humans
- Methylation
- Mutation
- RNA Processing, Post-Transcriptional
(genetics)
- RNA, Transfer
(genetics, metabolism)
- Saccharomyces cerevisiae
|
