Aristolochia indica green-synthesized silver nanoparticles: A sustainable control tool against the malaria vector Anopheles stephensi?

Abstract

Malaria is a life-threatening disease caused by parasites transmitted to people and animals through the bites of infected mosquitoes. We biosynthesized silver nanoparticles (AgNP) using Aristolochia indica extract as reducing and stabilizing agent. AgNP were characterized by UV-vis spectroscopy, FTIR, SEM, EDX and XRD. In laboratory, LC50 of A. indica extract against Anopheles stephensi ranged from 262.66 (larvae I) to 565.02 ppm (pupae). LC50 of AgNP against A. stephensi ranged from 3.94 (larvae I) to 15.65 ppm (pupae). In the field, the application of A. indica extract and AgNP (10 × LC50) leads to 100% larval reduction after 72 h. In laboratory, 24-h predation efficiency of Diplonychus indicus against A. stephensi larvae was 33% (larvae II) and 57% (larvae III). In AgNP-contaminated environment (1 ppm), it was 45.5% (larvae II) and 71.75% (larvae III). Overall, A. indica-synthesized AgNP may be considered as newer and safer control tools against Anopheles vectors.

• Authors: Kadarkarai Murugan, Mohammed Aamina Labeeba, Chellasamy Panneerselvam, Devakumar Dinesh, Udaiyan Suresh, Jayapal Subramaniam, Pari Madhiyazhagan, Jiang-Shiou Hwang, Lan Wang, Marcello Nicoletti, Giovanni Benelli
• Journal: Research in veterinary science (Res Vet Sci) Vol. 102 Pg. 127-35 (Oct 2015) ISSN: 1532-2661 [Electronic] England
• PMID: 26412532 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2015 Elsevier Ltd. All rights reserved.

Chemical References

• Insecticides
• Silver

Topics

• Animals
• Anopheles (drug effects)
• Aristolochia (metabolism)
• Green Chemistry Technology
• Insecticides (chemistry, metabolism, pharmacology)
• Larva (drug effects)
• Metal Nanoparticles (chemistry)
• Plant Leaves (metabolism)
• Silver (chemistry)