The antiviral activity of leaves of Eucalyptus camaldulensis (Dehn) and Eucalyptus torelliana (R. Muell).

Abstract

Human enteroviruses are the major cause of aseptic meningitis and are resistant to all known antibiotics and chemotherapeutic agents. Methanolic extracts of Eucalyptus camaldulensis and Eucalyptus torelliana were tested on human enteroviruses: Poliovirus type I, Coxsackievirus B and Echovirus 6. The virucidal tests showed that the crude extracts were active on the test viruses: poliovirus type 1, coxsackievirus B and echovirus 6 giving a neutralization index of one log and above. The cytotoxicity assay of the crude extracts to L20B (a genetically engineered mouse cell line) and human rhabdomyo sarcoma (RD) cells showed that the extract of E. torelliana was more toxic than the extract of E. camaldulensis. The antiviral study showed that the extract of E. torelliana was more active than that of E. camaldulensis.

• Authors: Bolanle Alake Adeniyi, Olayemi Oluseun Ayepola, Festus Doyin Adu
• Journal: Pakistan journal of pharmaceutical sciences (Pak J Pharm Sci) Vol. 28 Issue 5 Pg. 1773-6 (Sep 2015) ISSN: 1011-601X [Print] Pakistan
• PMID: 26408896 (Publication Type: Journal Article)

Chemical References

• Antiviral Agents
• Plant Extracts

Topics

• Animals
• Antiviral Agents (pharmacology)
• Eucalyptus (chemistry)
• Humans
• Mice
• Plant Extracts (pharmacology)
• Plant Leaves