Abstract |
Drug-induced gingival overgrowth (DIGO) is an oral clinical manifestation associated with certain medications such as immunosuppressants that are administered to organ transplant patients to prevent graft rejection. In patients with cardiac transplants, management of DIGO is critical. In such patients, plaque biofilm accumulation at the gingival interface might be detrimental as it may lead to transient bacteremia as well as systemic inflammation resulting in thromboembolic events. This case report describes the management of DIGO in a cardiac transplant recipient by change of immunosuppressant medication, non-surgical periodontal therapy and laser-assisted gingivectomy.
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Authors | Abhiram Maddi, Leela Subhashini Alluri, Sebastian G Ciancio |
Journal | Journal of the International Academy of Periodontology
(J Int Acad Periodontol)
Vol. 17
Issue 3
Pg. 77-81
(Jul 2015)
ISSN: 1466-2094 [Print] England |
PMID | 26373224
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Immunosuppressive Agents
- Cyclosporine
- Sirolimus
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Topics |
- Adult
- Cyclosporine
(adverse effects)
- Dental Scaling
(methods)
- Follow-Up Studies
- Gingival Overgrowth
(chemically induced, surgery)
- Gingivectomy
(methods)
- Gingivoplasty
(methods)
- Heart Transplantation
- Humans
- Immunosuppressive Agents
(adverse effects, therapeutic use)
- Laser Therapy
(methods)
- Lasers, Semiconductor
(therapeutic use)
- Male
- Oral Hygiene
(education)
- Root Planing
(methods)
- Sirolimus
(therapeutic use)
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