Abstract | INTRODUCTION: METHODS: A total of 1,367 adults of the population-based Cardiovascular Risk in Young Finns study (748 women, 619 men, aged 34-49 years) had fasting serum GGT, triglycerides, weight, height, and waist circumference, and self-reported TV time data from 2001, 2007, and 2011. Changes in GGT and FLI, and liver ultrasound images in 2011 were studied in groups with constantly low (≤ 1 h/d), moderate (1-3 h/d), or high (≥ 3 h/d) daily TV time, and in groups with ≥ 1 hour increase/decrease in daily TV time between 2001 and 2011. RESULTS: Constantly high TV time was associated with higher GGT and FLI (P < 0.02 in both), and 2.3-fold (95% CI 1.2-4.5) increased risk of fatty liver regardless of age, sex, leisure-time and occupational physical activity, energy intake, diet composition, alcohol use, sleep duration, socioeconomic status, and smoking. Adjustment for BMI partly attenuated the associations. CONCLUSIONS: High TV viewing increases fatty liver risk. It may be one mechanism linking sedentary behaviour with increased cardiometabolic disease risks.
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Authors | Harri Helajärvi, Katja Pahkala, Olli J Heinonen, Markus Juonala, Mervi Oikonen, Tuija Tammelin, Nina Hutri-Kähönen, Mika Kähönen, Terho Lehtimäki, Vera Mikkilä, Jorma Viikari, Olli T Raitakari |
Journal | Annals of medicine
(Ann Med)
Vol. 47
Issue 6
Pg. 519-26
( 2015)
ISSN: 1365-2060 [Electronic] England |
PMID | 26362414
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Triglycerides
- gamma-Glutamyltransferase
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Topics |
- Adult
- Body Mass Index
- Body Weight
- Cardiovascular Diseases
(blood, epidemiology)
- Female
- Finland
(epidemiology)
- Humans
- Longitudinal Studies
- Male
- Middle Aged
- Non-alcoholic Fatty Liver Disease
(blood, diagnostic imaging, epidemiology)
- Risk Factors
- Sedentary Behavior
- Television
(statistics & numerical data)
- Triglycerides
(blood)
- Ultrasonography
- Waist Circumference
- gamma-Glutamyltransferase
(blood)
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