Abstract | BACKGROUND: Supplementation with B vitamins for stroke prevention has been evaluated over the years, but which combination of B vitamins is optimal for stroke prevention is unclear. We performed a network meta-analysis to assess the impact of different combinations of B vitamins on risk of stroke. METHODS: A total of 17 trials (86 393 patients) comparing 7 treatment strategies and placebo were included. A network meta-analysis combined all available direct and indirect treatment comparisons to evaluate the efficacy of B vitamin supplementation for all interventions. RESULTS: CONCLUSIONS:
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Authors | Hongli Dong, Fuhua Pi, Zan Ding, Wei Chen, Shaojie Pang, Wenya Dong, Qingying Zhang |
Journal | PloS one
(PLoS One)
Vol. 10
Issue 9
Pg. e0137533
( 2015)
ISSN: 1932-6203 [Electronic] United States |
PMID | 26355679
(Publication Type: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't)
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Chemical References |
- Vitamin B Complex
- Vitamin B 6
- Vitamin B 12
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Topics |
- Bayes Theorem
- Dietary Supplements
- Humans
- Randomized Controlled Trials as Topic
- Risk
- Stroke
(drug therapy, epidemiology, prevention & control)
- Treatment Outcome
- Vitamin B 12
(administration & dosage)
- Vitamin B 6
(administration & dosage)
- Vitamin B Complex
(administration & dosage)
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