Mediastinal Fibrosis of the Pulmonary Artery Secondary to Tuberculosis.

Abstract

Mediastinal fibrosis is an uncommon disease involving the esophagus, respiratory tract, and great vessels. We report a man who presented with dyspnea on exertion. Computed tomography of the chest demonstrated granulomatous disease with dense calcifications leading to severe stenosis of the main pulmonary artery (PA) and narrowing of the superior vena cava. The results of tuberculosis (TB) interferon-γ release assay and TB-polymerase chain reaction were positive for Mycobacterium tuberculosis. The patient received 2 weeks of treatment for latent TB before undergoing resection of fibrotic tissue and replacement of the main and branch PAs using a homograft.

• Authors: Oluseyi Ojeifo, Nisha A Gilotra, Clinton D Kemp, Andrew Leventhal, Jon Resar, Kenton J Zehr, Steve Jones
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 100 Issue 3 Pg. e49-50 (Sep 2015) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 26354666 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Topics

• Arterial Occlusive Diseases (microbiology)
• Fibrosis (microbiology)
• Humans
• Male
• Mediastinum (pathology)
• Middle Aged
• Pulmonary Artery
• Tuberculosis, Pulmonary (complications)