Abstract |
Reported are the results of a retrospective study of 3156 patients who were treated at the Queen Saovabha Memorial Institute, Bangkok, with equine rabies immune globulin (ERIG). Only 51 patients (1.6%) exhibited serum-sickness-like reactions, none of which persisted for more than a week, and only 8 of these patients (15%) were treated with a short course of steroids. One patient, whose skin test was negative, had an immediate anaphylactic reaction to ERIG that responded to parenteral therapy with epinephrine and hydrocortisone sodium succinate. Serum-sickness-like reactions were more frequent among females and over 21-year-olds but were exceedingly rare (0.086%) among children under 10 years of age.
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Authors | H Wilde, P Chomchey, P Punyaratabandhu, P Phanupak, S Chutivongse |
Journal | Bulletin of the World Health Organization
(Bull World Health Organ)
Vol. 67
Issue 6
Pg. 731-6
( 1989)
ISSN: 0042-9686 [Print] Switzerland |
PMID | 2633888
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Anaphylaxis
(etiology)
- Animals
- Child
- Female
- Horses
(immunology)
- Humans
- Immunization, Passive
(adverse effects)
- Male
- Middle Aged
- Rabies
(therapy)
- Rabies Vaccines
(adverse effects, therapeutic use)
- Rabies virus
(immunology)
- Retrospective Studies
- Serum Sickness
(etiology)
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