Abstract | BACKGROUND: PATIENTS AND METHODS: 28 patients with hypopigmented scars were divided randomly into two groups. The patients in group A were treated in six sessions (1-month intervals) with 10600-nm fractional CO2 laser plus latanoprost 0.005% and those of group B fractionated CO2 laser plus placebo (distilled water). Digital photographs were taken at baseline and 3 months after the last treatment session. The blinded dermatologist compared the photographs and evaluated the efficacy of treatment in the hypopigmented scars using a 4-scale point (grade 1-4). Patient satisfaction was scored from 0 to 10 on a visual analog scale. RESULTS: Follow-up results 12 weeks after the last treatment session demonstrated that 11 of the 14 patients in group A had more than 50% improvement in hypopigmentation The difference in improvement of the two groups was statistically significant (P = 0.027). The mean of the VAS scores of patients in group A was 6.50 ± 1.45 and in group B 4.57 ± 1.6. The difference in mean satisfaction of the two groups was statistically significant (P = 0.003). Side effects were mild and resolved within 1 to 5 days. CONCLUSION: The fractional CO2 laser resurfacing plus topical latanoprost can be used as a safe and efficacious method to treat hypopigmented scars.
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Authors | Amir Hossein Siadat, Reza Rezaei, Ali Asilian, Bahareh Abtahi-Naeini, Mehrdad Rakhshanpour, Mehdi Raei, Seyed Mohsen Hosseini |
Journal | Indian journal of dermatology
(Indian J Dermatol)
2015 Jul-Aug
Vol. 60
Issue 4
Pg. 364-8
ISSN: 1998-3611 [Electronic] India |
PMID | 26288404
(Publication Type: Journal Article)
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