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Isotonic vs Hypotonic Intravenous Fluids for Hospitalized Children.

AbstractCLINICAL QUESTION:
Is isotonic fluid associated with a lower incidence of hyponatremia when compared with hypotonic fluid for maintenance intravenous fluid therapy in children?
BOTTOM LINE:
Compared with hypotonic fluid, isotonic fluid is associated with a lower incidence of hyponatremia, without evidence of an increase in adverse outcomes.
AuthorsSarah McNab
JournalJAMA (JAMA) Vol. 314 Issue 7 Pg. 720-1 (Aug 18 2015) ISSN: 1538-3598 [Electronic] United States
PMID26284724 (Publication Type: Journal Article, Comment)
Chemical References
  • Hypotonic Solutions
  • Isotonic Solutions
  • Saline Solution, Hypertonic
Topics
  • Fluid Therapy (adverse effects)
  • Humans
  • Hyponatremia (etiology)
  • Hypotonic Solutions (adverse effects)
  • Isotonic Solutions (adverse effects)
  • Saline Solution, Hypertonic (adverse effects)

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