Folliculotropic Mycosis Fungoides as a Posttransplant Lymphoproliferative Disorder.

Abstract

Posttransplant lymphoproliferative disorder (PTLD) is a known complication of solid organ transplantation. The majority are B cell in origin and related to Epstein-Barr virus infection. T-cell PTLD is much less common; most are Epstein-Barr virus negative and have a worse prognosis. Primary cutaneous T-cell lymphoma (CTCL) as a presentation of PTLD is rare. CTCL has a less favorable prognosis in transplant patients compared with that in immune-competent patients. Herein, we report a case of a 13-year-old boy who developed folliculotropic mycosis fungoides, a rare subtype of CTCL, subsequent to renal transplantation. To our knowledge, this is the first report of this type of PTLD in a pediatric patient.

• Authors: Allyson Spence-Shishido, Jenna L Streicher, Roshan P George, Sareeta R Parker, Leslie P Lawley
• Journal: Pediatrics (Pediatrics) Vol. 136 Issue 3 Pg. e701-5 (Sep 2015) ISSN: 1098-4275 [Electronic] United States
• PMID: 26283779 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 by the American Academy of Pediatrics.

Chemical References

• Immunosuppressive Agents

Topics

• Adolescent
• Humans
• Immunocompromised Host
• Immunosuppressive Agents (adverse effects)
• Kidney Transplantation (adverse effects)
• Male
• Mycosis Fungoides (etiology, therapy)
• Skin Neoplasms (etiology, therapy)