[In vitro susceptibility of dermatophyte strains to imidazole derivatives].

Recently, imidazole derivatives are being successfully used for the dermatomycoses. These drugs have the strongest antimycotic activity. 44 dermatophyte strains were isolated from our out-patient with dermatomycosis. Imidazole derivatives such as isoconazole, oxiconazole, bifonazole and tioconazole were studied their efficacy on these fungal agents in vitro. 4 imidazole derivatives were effective on all of the dermatophyte strains in less than or equal to 5 micrograms/ml concentration. Whereas, there were differences in Minimal Inhibition Concentration (MIC) and MIC50 values.
AuthorsM Bozkurt, S Kuştimur, M A Gürer
JournalMikrobiyoloji bülteni (Mikrobiyol Bul) Vol. 23 Issue 1 Pg. 64-70 (Jan 1989) ISSN: 0374-9096 [Print] TURKEY
Vernacular TitleDermatofit suşlarinin imidazol türevlerine karşi invitro duyarliliği.
PMID2626098 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antifungal Agents
  • Imidazoles
  • bifonazole
  • Miconazole
  • oxiconazole
  • isoconazole
  • tioconazole
  • Antifungal Agents (pharmacology)
  • Arthrodermataceae (drug effects)
  • Dermatomycoses (drug therapy, microbiology)
  • Humans
  • Imidazoles (pharmacology, therapeutic use)
  • Miconazole (analogs & derivatives, pharmacology)

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