Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.

Abstract

Allergic reactions to drugs are a serious public health concern. In 2013, the Division of Allergy, Immunology, and Transplantation of the National Institute of Allergy and Infectious Diseases sponsored a workshop on drug allergy. International experts in the field of drug allergy with backgrounds in allergy, immunology, infectious diseases, dermatology, clinical pharmacology, and pharmacogenomics discussed the current state of drug allergy research. These experts were joined by representatives from several National Institutes of Health institutes and the US Food and Drug Administration. The participants identified important advances that make new research directions feasible and made suggestions for research priorities and for development of infrastructure to advance our knowledge of the mechanisms, diagnosis, management, and prevention of drug allergy. The workshop summary and recommendations are presented herein.

• Authors: Lisa M Wheatley, Marshall Plaut, Julie M Schwaninger, Aleena Banerji, Mariana Castells, Fred D Finkelman, Gerald J Gleich, Emma Guttman-Yassky, Simon A K Mallal, Dean J Naisbitt, David A Ostrov, Elizabeth J Phillips, Werner J Pichler, Thomas A E Platts-Mills, Jean-Claude Roujeau, Lawrence B Schwartz, Lauren A Trepanier
• Journal: The Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 136 Issue 2 Pg. 262-71.e2 (Aug 2015) ISSN: 1097-6825 [Electronic] United States
• PMID: 26254053 (Publication Type: Consensus Development Conference, NIH, Journal Article)
• Copyright: Published by Elsevier Inc.

Chemical References

• Dideoxynucleosides
• HLA Antigens
• Haptens
• Receptors, Antigen, T-Cell
• Carbamazepine
• Immunoglobulin E
• abacavir

Topics

• Carbamazepine (adverse effects)
• Dideoxynucleosides (adverse effects)
• Drug Hypersensitivity (diagnosis, epidemiology, etiology, prevention & control)
• Gene Expression
• HLA Antigens (genetics, immunology)
• Haptens (immunology)
• Humans
• Immunoglobulin E (blood)
• National Institute of Allergy and Infectious Diseases (U.S.)
• Practice Guidelines as Topic
• Receptors, Antigen, T-Cell (genetics, immunology)
• Stevens-Johnson Syndrome (diagnosis, epidemiology, etiology, prevention & control)
• Terminology as Topic
• Translational Research, Biomedical (trends)
• United States (epidemiology)
• Virus Diseases (diagnosis, epidemiology, immunology, prevention & control)