Abstract |
The long QT syndrome is caused by a change in cardiac repolarization due to functional ion channel defects. A differentiation is made between a congenital (cLQTS) and an acquired (aLQTS) form of the disease. The disease results in the name-giving prolongation of the QT interval in the electrocardiogram and represents a predisposition for cardiac arrhythmia and sudden cardiac death. This article summarizes the current knowledge on the history, pathophysiology, clinical symptoms and therapy of cLQTS and aLQTS. This knowledge of pathophysiological features of the symptoms allows the underlying anesthesiological approach for individualized perioperative concepts for patients suffering from LQTS to be derived.
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Authors | T Krönauer, P Friederich |
Journal | Der Anaesthesist
(Anaesthesist)
Vol. 64
Issue 8
Pg. 586-95
(Aug 2015)
ISSN: 1432-055X [Electronic] Germany |
Vernacular Title | Long-QT-Syndrom. Historie, Genetik, klinische Symptome, Ursachen und Therapie. |
PMID | 26250931
(Publication Type: English Abstract, Historical Article, Journal Article, Review)
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Topics |
- Arrhythmias, Cardiac
(etiology, therapy)
- Death, Sudden, Cardiac
(etiology, prevention & control)
- Electrocardiography
- History, 20th Century
- History, 21st Century
- Humans
- Long QT Syndrome
(complications, genetics, history, therapy)
- Perioperative Care
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