Abstract | BACKGROUND: METHODOLOGY: We reviewed the records of 164 consecutive HL patients. RESULTS: BPT was observed in 24 of 164 patients (15%). Older age and history of concomitant lung disease were significantly associated with approximately threefold (odds ratio: 3.38; 95% CI: 1.25-9.13; p = 0.02) and sevenfold (odds ratio: 7.19; 95% CI: 2.64-19.54; p < 0.0001) increase in BPT risk, respectively. The actuarial 5-year progression-free and overall survival for BPT and non-BPT groups, were not significantly different. CONCLUSION: In Saudi Arabian HL patients, the risk of BPT and its effect on survival outcome were comparable to that reported from developed countries.
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Authors | Wafa'a A Al-Jizani, Mubarak M Al-Mansour, Turki M Al-Fayea, Ruaa U Shafi, Ghieth A Kazkaz, Ali M Bayer, Meteb E Al-Foheidi, Ezzeldin M Ibrahim |
Journal | Future oncology (London, England)
(Future Oncol)
Vol. 11
Issue 15
Pg. 2149-57
( 2015)
ISSN: 1744-8301 [Electronic] England |
PMID | 26235180
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Bleomycin
(administration & dosage, adverse effects)
- Disease-Free Survival
- Female
- Hodgkin Disease
(complications, drug therapy, pathology)
- Humans
- Lung
(drug effects, physiopathology)
- Lung Diseases
(chemically induced, physiopathology)
- Male
- Middle Aged
- Saudi Arabia
- Treatment Outcome
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