Abstract |
A 25-year-old man with human immunodeficiency virus ( HIV) infection presented with fever that had lasted 1 month. The CD4+ T lymphocyte count was 7 cells/μL and computed tomography showed several small lung nodules, splenomegaly, and multiple lymphadenopathy. Talaromyces marneffei was isolated in the initial blood cultures. As the fever persisted despite clearance of fungemia and 10 days of liposomal amphotericin B treatment, cervical lymph node fine-needle aspiration was performed. Mycobacterium intracellulare was isolated from sputum and neck node aspiration cultures. The patient was successfully treated with liposomal amphotericin B, clarithromycin, and ethambutol in addition to antiretroviral therapy. This case suggests that we should consider coinfection of opportunistic pathogens in febrile immunosuppressed patients if the patient does not respond properly to the initial treatment.
|
Authors | Hyeri Seok, Jae-Hoon Ko, Inseub Shin, Young Hee Eun, Seung-Eun Lee, You-Bin Lee, Kyong Ran Peck |
Journal | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
(Int J Infect Dis)
Vol. 38
Pg. 86-8
(Sep 2015)
ISSN: 1878-3511 [Electronic] Canada |
PMID | 26232630
(Publication Type: Case Reports, Journal Article)
|
Copyright | Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved. |
Topics |
- Adult
- Coinfection
(complications, diagnosis, drug therapy)
- Fungemia
(complications, diagnosis, drug therapy)
- HIV Infections
(complications, drug therapy)
- Humans
- Male
- Mycobacterium avium Complex
(isolation & purification)
- Mycobacterium avium-intracellulare Infection
(complications, diagnosis, drug therapy)
- Talaromyces
(isolation & purification)
|