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Ochronotic arthritis of bilateral knees: a case report.

Abstract
Alkaptonuria ochronosis is a rare metabolic disease in which the body does not have enough enzyme called homogentisic acid oxidase. Due to the homogentisic acid oxidase deficiency, homogentisic acid accumulates in cartilage and connective tissues which leads to ochronotic arthritis. We reported a case of bilateral ochronotic arthritis verified by clinical presentation, imaging, arthroscopic and histological findings. The patient achieved a satisfying therapeutic outcome after arthroscopic debridement followed by intra-articular injection of sodium haluronate.
AuthorsHang Xu, Jianzhao Wang, Fuying Chen, Zengchao Hong, Xiaoyang Zhang, Xiaohui Ji, Decheng Shao
JournalInternational journal of clinical and experimental medicine (Int J Clin Exp Med) Vol. 8 Issue 5 Pg. 8185-9 ( 2015) ISSN: 1940-5901 [Print] United States
PMID26221390 (Publication Type: Case Reports)

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