Abstract | INTRODUCTION: Aneurysmal bone cyst is a benign bone lesion composed of blood filled cystic cavities lined by fibrous septa. Its malignant transformation of is a rare event. CASE REPORT: We report a case of a lesion in the second metatarsal bone in a 29-year-old male, presented as a slight swelling of the right foot. After the curettage had been done, the diagnosis of aneurysmal bone cyst was made but the recurrence occurred 4 years later. The biopsy of the recurrent tumor showed compact neoplastic tissue consistent with diagnosis of giant cell tumor with malignancy. The malignant component was recognized as a high grade sarcoma with osteoid production. A tumor mass with the whole II metatarsal bone was extirpated and a resected part of fibula was transplanted. A year later, another recurrence occurred, an amputation was performed and a teleangiectatic osteosarcoma with ingvinal lymph nodes metastases was diagnosed. No other tumor mass was confirmed, either clinically or by imaging techniques at the time of his third operation. He died 4 months later with multiple pulmonary metastases. CONCLUSION: We emphasize the importance of team work in order to achieve the accurate diagnosis, highlighting careful radiological examinations, good sampling and awareness of unusual cases in bone tumor pathology.
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Authors | Vesna Janevska, Liljana Spasevska, Milan Samardziski, Violeta Nikodinovskai, Julija Zhivadinovik, Elizabeta Trajkovskai |
Journal | Medicinski pregled
(Med Pregl)
2015 Mar-Apr
Vol. 68
Issue 3-4
Pg. 127-32
ISSN: 0025-8105 [Print] Serbia |
PMID | 26214993
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adult
- Biopsy
- Bone Cysts, Aneurysmal
(pathology)
- Bone Neoplasms
(pathology)
- Fatal Outcome
- Humans
- Lung Neoplasms
(secondary)
- Lymphatic Metastasis
(pathology)
- Male
- Metatarsal Bones
(pathology)
- Neoplasm Recurrence, Local
(pathology)
- Osteosarcoma
(pathology)
- Telangiectasis
(pathology)
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