A case of lacrimal sarcoidosis following interstitial pneumonia: imaging and management.

Abstract

A 60-year-old Japanese man developed a fever and dry cough. Although chest CT showed interstitial pneumonia, the primary disease was not revealed. The interstitial pneumonia was improved by treatment with oral prednisolone following methylprednisolone pulse therapy. After the discontinuation of prednisolone he developed swelling of the eyelids and polyarthralgia. Orbital magnetic resonance imaging showed enlargement of the bilateral lacrimal glands. (67)Gallium scintigraphy showed abnormal uptake of the bilateral lacrimal glands and pulmonary hilum. A lacrimal gland biopsy showed noncaseating granulomatous infiltration with occasional multinucleated giant cells consistent with sarcoidosis. His symptoms improved by treatment with oral prednisolone and triamcinolone injection into the lacrimal glands.

• Authors: Shin-ya Kawashiri, Hideki Nakamura, Tomoki Origuchi, Kiyoshi Aoyagi, Atsushi Kawakami
• Journal: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology (Nihon Rinsho Meneki Gakkai Kaishi) Vol. 38 Issue 3 Pg. 164-8 ( 2015) ISSN: 1349-7413 [Electronic] Japan
• PMID: 26213195 (Publication Type: Case Reports, Journal Article)

Chemical References

• Triamcinolone
• Prednisolone

Topics

• Humans
• Injections, Intralesional
• Lacrimal Apparatus
• Lung Diseases, Interstitial (complications)
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Prednisolone (administration & dosage)
• Radionuclide Imaging
• Sarcoidosis (diagnosis, diagnostic imaging, drug therapy)
• Triamcinolone (administration & dosage)