Expression of elastic fiber in esophageal squamous carcinoma tissue.

Abstract

AIM:

We studied the expression of elastic fiber in esophageal squamous cell carcinoma tissue in North-eastern Indian population.

MATERIALS AND METHODS:

Archival paraffin embedded 40 esophageal carcinoma specimens were retrieved for the study. Only smokers were included in the study. Verhoeff's stain for elastic fiber was performed to demonstrate elastic fiber with positive and negative control.

RESULT:

A total of 28 (70%) tissue specimens was found to be positive for elastic fiber.

CONCLUSION:

Elastosis in esophageal carcinoma may be due to smoking. Further studies are required to rule out the etiology.

• Authors: Akshay Chandra Deka, Vidhya Srinivasan, Ananta Madhab Dutta, Pratap Chandra Sarma
• Journal: Journal of cancer research and therapeutics (J Cancer Res Ther) 2015 Apr-Jun Vol. 11 Issue 2 Pg. 277-9 ISSN: 1998-4138 [Electronic] India
• PMID: 26148584 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adult
• Aged
• Carcinoma, Squamous Cell (metabolism, pathology)
• Elastic Tissue (metabolism, pathology)
• Esophageal Neoplasms (metabolism, pathology)
• Esophageal Squamous Cell Carcinoma
• Female
• Humans
• Immunohistochemistry
• Male
• Middle Aged