Abstract | INTRODUCTION: METHODS: We conducted a retrospective chart review of consecutive patients with PD who were admitted to the Department of Neurology, Juntendo University School of Medicine between January 2010 and July 2014. One hundred and sixty-seven patients with PD who underwent gradient echo T2*-weighted magnetic resonance imaging of the brain were included in the present study. A multivariate logistic regression analysis was performed to investigate the associations between risk factors and the presence of CMBs. RESULTS: CMBs were detected in 29 (17.4%) patients. Among the patients with CMBs, 19 (65.5%) had deep or infratentorial CMBs and 10 (34.5%) had strictly lobar CMBs. Hypertension, OH and a history of ischemic stroke were independently associated with deep or infratentorial CMBs, whereas antiplatelet use was independently associated with strictly lobar CMBs. CONCLUSIONS: In patients with PD, deep or infratentorial CMBs were more frequent than strictly lobar CMBs, and were associated with hypertension, OH and a history of ischemic stroke.
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Authors | Kazuo Yamashiro, Ryota Tanaka, Yasunobu Hoshino, Taku Hatano, Kenya Nishioka, Nobutaka Hattori |
Journal | Parkinsonism & related disorders
(Parkinsonism Relat Disord)
Vol. 21
Issue 9
Pg. 1076-81
(Sep 2015)
ISSN: 1873-5126 [Electronic] England |
PMID | 26142208
(Publication Type: Journal Article)
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Copyright | Copyright © 2015 Elsevier Ltd. All rights reserved. |
Topics |
- Aged
- Aged, 80 and over
- Brain
(pathology)
- Cerebral Hemorrhage
(complications, diagnosis, epidemiology)
- Female
- Humans
- Hypertension
(epidemiology)
- Logistic Models
- Magnetic Resonance Imaging
- Male
- Parkinson Disease
(complications, epidemiology)
- Prevalence
- Retrospective Studies
- Risk Factors
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