Abstract | INTRODUCTION: CASE PRESENTATION: CONCLUSION: Incidence, differential diagnosis, diagnostic procedures, pathologic findings and treatment of splenic hamartomas are discussed here and hamartomas are considered in a differential diagnosis of splenic tumors. A splenectomy is indicated in cases where malignancy cannot be excluded and in cases of associated hematologic disorders. To the best of our knowledge our patient is the first reported case to have splenic hamartomas identified in a familial adenomatous polyposis-affected patient with mutation in exon 15 of the APC gene. At this time it is not possible to correlate with certainty our multiple splenic hamartomas and familial adenomatous polyposis case as a clinical manifestation of the mutation of APC gene; however, we believe that this case report could be important for further observation of similar cases in the future.
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Authors | Nicola Carlomagno, Francesca Duraturo, Maria Candida, Marina De Rosa, Valeria Varone, Giuseppe Ciancia, Armando Calogero, Michele L Santangelo |
Journal | Journal of medical case reports
(J Med Case Rep)
Vol. 9
Pg. 154
(Jul 04 2015)
ISSN: 1752-1947 [Electronic] England |
PMID | 26141168
(Publication Type: Case Reports, Journal Article, Review)
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Topics |
- Adenomatous Polyposis Coli
(complications, diagnostic imaging, surgery)
- Diagnosis, Differential
- Female
- Hamartoma
(complications, diagnostic imaging, surgery)
- Humans
- Middle Aged
- Spleen
(diagnostic imaging, surgery)
- Splenectomy
- Splenic Diseases
(complications, diagnostic imaging, surgery)
- Tomography, X-Ray Computed
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