Diffuse idiopathic skeletal hyperostosis and isotretinoin in cystic acne.

Abstract

We present the case of a 35-year-old man with thoracic back pain and stiffness, whose only medical history was cystic acne treated with repeated courses of retinoids. His thoracic spine was severely limited in range of movement and was found, on X-ray, to have unilateral hyperostosis typical of diffuse idiopathic skeletal hyperostosis (DISH)--an often asymptomatic condition rarely found in those under 50. Back stiffness in young patients with prolonged retinoid exposure should be investigated.

• Authors: Sizheng Zhao, Nicola J Goodson
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2015 (Jun 23 2015) ISSN: 1757-790X [Electronic] England
• PMID: 26106176 (Publication Type: Case Reports, Journal Article)
• Copyright: 2015 BMJ Publishing Group Ltd.

Chemical References

• Analgesics
• Dermatologic Agents
• Isotretinoin

Topics

• Acne Vulgaris (drug therapy)
• Adult
• Analgesics (therapeutic use)
• Back Pain (drug therapy, etiology)
• Dermatologic Agents (administration & dosage, adverse effects)
• Diagnosis, Differential
• Drug Administration Schedule
• Humans
• Hyperostosis, Diffuse Idiopathic Skeletal (chemically induced, complications, diagnostic imaging, drug therapy)
• Isotretinoin (administration & dosage, adverse effects)
• Male
• Radiography
• Thoracic Vertebrae (diagnostic imaging)