[Pharmacotherapy of psoriatic arthritis. Treatment recommendations against the background of limited evidence].

Abstract

International treatment recommendations for assisting the choice of pharmaceutical treatment of psoriatic arthritis are currently available in two different versions. While the group for research and assessment of psoriasis and psoriatic arthritis (GRAPPA) recommendations mainly focus on both the description of treatment options for the different phenotypes of psoriatic arthritis and the listing of evidence grades, the European League against Rheumatism (EULAR) recommendations try to implement the knowledge about drugs into an algorithm for the different treatment steps. However, the presentation of a treatment algorithm suggests comparable evidence levels for the individual treatment steps, which is at present not the case for psoriatic arthritis. This should be borne in mind for each individual treatment option and treatment step when using a predetermined therapy algorithm and in view of the heterogeneous study results (or no study results available). Both recommendations are currently being revised and will allow the latest evidence trends to be included in the updated version.

• Authors: M Köhm, F Behrens
• Journal: Zeitschrift fur Rheumatologie (Z Rheumatol) Vol. 74 Issue 5 Pg. 398-405 (Jun 2015) ISSN: 1435-1250 [Electronic] Germany
• Vernacular Title: Pharmakotherapie der Psoriasisarthritis. Behandlungsempfehlungen vor dem Hintergrund limitierter Evidenzen.
• PMID: 26085072 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Biological Products
• Immunosuppressive Agents

Topics

• Adrenal Cortex Hormones (administration & dosage)
• Arthritis, Psoriatic (diagnosis, drug therapy)
• Biological Products (administration & dosage)
• Combined Modality Therapy (methods)
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Europe
• Evidence-Based Medicine
• Humans
• Immunosuppressive Agents (administration & dosage)
• PUVA Therapy (methods)
• Practice Guidelines as Topic
• Rheumatology (standards)
• Treatment Outcome