Abstract | PURPOSE: METHODS: RESULTS: Baseline best-corrected visual acuity was 20/160 and improved statistically significantly to 20/80 and 20/60 at 1 months and 3 months, respectively (P < 0.05, both postoperative visits), and 20/100 at 6 months (P > 0.05). The central macular thickness at baseline was 569.96 ± 178.11 μm, and it decreased statistically significantly to 305.81 ± 155.94 μm, 386 ± 210.79 μm, and 446.41 ± 221.21 μm at 1, 3 and 6 months, respectively (P < 0.05, all visits compared with baseline). Fourteen (26%) eyes developed high intraocular pressure after implantation and was successfully controlled with topical medications, and cataract progressed in 1 (1.8%) eye. CONCLUSION: The dexamethasone implant improved macular edema in refractory cases resulting in statistically significant improvements in best-corrected visual acuity and central macular thickness that remained stable to 3 months and 6 months, respectively.
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Authors | Saeed T Alshahrani, Rosa Dolz-Marco, Roberto Gallego-Pinazo, Manuel Diaz-Llopis, J Fernando Arevalo, KKESH International Collaborative Retina Study Group |
Journal | Retina (Philadelphia, Pa.)
(Retina)
Vol. 36
Issue 1
Pg. 131-6
(Jan 2016)
ISSN: 1539-2864 [Electronic] United States |
PMID | 26079477
(Publication Type: Journal Article)
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Chemical References |
- Drug Implants
- Glucocorticoids
- Dexamethasone
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Dexamethasone
(administration & dosage)
- Diabetic Retinopathy
(complications, drug therapy, physiopathology)
- Drug Implants
- Female
- Glucocorticoids
(administration & dosage)
- Humans
- Intraocular Pressure
(physiology)
- Intravitreal Injections
- Macular Edema
(drug therapy, etiology, physiopathology)
- Male
- Middle Aged
- Retina
(pathology)
- Retinal Vein Occlusion
(complications, drug therapy, physiopathology)
- Retrospective Studies
- Tomography, Optical Coherence
- Tonometry, Ocular
- Visual Acuity
(physiology)
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