Secretory breast carcinoma in a 41-year-old man with long-term follow-up: a special report.

Abstract

Secretory breast carcinoma (SBC) is a rare tumor that is particularly rare in male adults. To our knowledge, only 28 previous male cases of secretory breast carcinoma have been reported. The present a case of secretory breast carcinoma has the longest symptom duration of (40 years) in a male individual until now. Typically, the clinical features and treatment of male SBC are similar with female SBC. The ETV6-NTRK3 fusion gene is a specific genetic alteration in SBC. When compared to other types of male breast cancer, patients with male secretory breast cancer are much younger, and have a lower rate of estrogen/progesterone hormone receptor positivity. Modified radical mastectomy has been favored as a therapeutic approach in all female SBC, male SBC and other types of male breast cancer. [corrected].

• Authors: Guanqiao Li, Xiaojie Zhong, Jia Yao, Jimin Chen, Mei Wang, Haiying Liu, Shiping Yang
• Journal: Future oncology (London, England) (Future Oncol) Vol. 11 Issue 12 Pg. 1767-73 ( 2015) ISSN: 1744-8301 [Electronic] England
• PMID: 26075445 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adult
• Breast Neoplasms (diagnostic imaging, pathology, surgery)
• Breast Neoplasms, Male (diagnostic imaging, pathology, surgery)
• Carcinoma (diagnostic imaging, pathology, surgery)
• Follow-Up Studies
• Humans
• Male
• Ultrasonography