Abstract | PURPOSE: MATERIALS AND METHODS: A MEDLINE (PubMed) search from January 1990 to April 2015 was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search was restricted to the English language and human subjects. Inclusion criteria were patients with HPS who underwent TIPS creation for any indication. Exclusion criteria was age < 18 years. RESULTS: Ten studies consisting of 12 patients with HPS were included. Eight patients had very severe HPS, 2 had severe HPS, and 2 had moderate HPS. Transjugular intrahepatic portosystemic shunt creation was technically successful in all patients, without complications. Mean portosystemic pressure gradients before and after the procedure were 18.2 mm Hg (range, 10-30 mm Hg) and 6.5 mm Hg (range, 3-15 mm Hg), respectively. The mean duration of follow-up was 9.3 months (range, 0.75-36 mo). Improvement in oxygenation occurred in 9 patients but was not sustained after 4 months in 2 patients. In the remaining 3 patients, oxygenation remained unchanged; it worsened after 4 months in 1 patient. Four patients underwent liver transplantation. Two patients died of multiple organ dysfunction syndrome and 1 died of sepsis. The remaining patients were alive and well at the time of last follow-up. CONCLUSIONS: Transjugular intrahepatic portosystemic shunt creation shows promise in the management of HPS. Future prospective studies are warranted.
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Authors | Jiaywei Tsauo, Ningna Weng, Huaiyuan Ma, Mingshan Jiang, He Zhao, Xiao Li |
Journal | Journal of vascular and interventional radiology : JVIR
(J Vasc Interv Radiol)
Vol. 26
Issue 9
Pg. 1266-71
(Sep 2015)
ISSN: 1535-7732 [Electronic] United States |
PMID | 26074026
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Copyright | Copyright © 2015 SIR. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Hepatopulmonary Syndrome
(diagnosis, surgery)
- Humans
- Middle Aged
- Portasystemic Shunt, Transjugular Intrahepatic
(adverse effects, methods)
- Postoperative Complications
(diagnosis, etiology)
- Treatment Outcome
- Young Adult
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