[The platelet factor 4 content of the blood in induced myocardial ischemia in patients with stable stenocardia].

Abstract

Seventeen patients were studied: 10 with stable angina and coronary atherosclerosis, and 7 with "intact" coronary arteries (a control group). All patients underwent coronarography and catheterization of the coronary sinus. Blood samples were obtained from the left ventricle and coronary sinus in 3 points: at rest, peak pacing, 10 min after pacing. All patients with stable angina had positive atrial pacing test (pain and/or ECG deviations and lactate production), in control group similar changes were not observed. However, no statistically significant difference was found in platelet factor (IV) 4 levels between the groups and following pacing; the level of platelet factor IV was near 90 ng/ml. It is concluded that patients with stable angina during pacing-induced ischemia had no significant platelet activation, which may provoke thrombotic events.

• Authors: N A Pavlov, E V Pomerantsev, V P Masenko, T I Kupriianenko
• Journal: Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR (Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR) Vol. 12 Issue 2 Pg. 69-71 ( 1989) ISSN: 0201-7369 [Print] Russia (Federation)
• Vernacular Title: Soderzhanie 4-go faktora trombotsitov v krovi na fone indutsirovannoĭ ishemii miokarda u bol'nykh stabil'noĭ stenokardieĭ.
• PMID: 2604890 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Platelet Factor 4

Topics

• Adult
• Angina Pectoris (blood, complications)
• Coronary Disease (blood, etiology)
• Female
• Humans
• Male
• Middle Aged
• Neurocirculatory Asthenia (blood)
• Osteochondritis (blood)
• Platelet Activation (physiology)
• Platelet Factor 4 (analysis)
• Spondylitis (blood)