[The platelet factor 4 content of the blood in induced myocardial ischemia in patients with stable stenocardia].

Seventeen patients were studied: 10 with stable angina and coronary atherosclerosis, and 7 with "intact" coronary arteries (a control group). All patients underwent coronarography and catheterization of the coronary sinus. Blood samples were obtained from the left ventricle and coronary sinus in 3 points: at rest, peak pacing, 10 min after pacing. All patients with stable angina had positive atrial pacing test (pain and/or ECG deviations and lactate production), in control group similar changes were not observed. However, no statistically significant difference was found in platelet factor (IV) 4 levels between the groups and following pacing; the level of platelet factor IV was near 90 ng/ml. It is concluded that patients with stable angina during pacing-induced ischemia had no significant platelet activation, which may provoke thrombotic events.
AuthorsN A Pavlov, E V Pomerantsev, V P Masenko, T I Kupriianenko
JournalBiulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR (Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR) Vol. 12 Issue 2 Pg. 69-71 ( 1989) ISSN: 0201-7369 [Print] USSR
Vernacular TitleSoderzhanie 4-go faktora trombotsitov v krovi na fone indutsirovannoń≠ ishemii miokarda u bol'nykh stabil'noń≠ stenokardień≠.
PMID2604890 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Platelet Factor 4
  • Adult
  • Angina Pectoris (blood, complications)
  • Coronary Disease (blood, etiology)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurocirculatory Asthenia (blood)
  • Osteochondritis (blood)
  • Platelet Activation (physiology)
  • Platelet Factor 4 (analysis)
  • Spondylitis (blood)

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