HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

[The platelet factor 4 content of the blood in induced myocardial ischemia in patients with stable stenocardia].

Abstract
Seventeen patients were studied: 10 with stable angina and coronary atherosclerosis, and 7 with "intact" coronary arteries (a control group). All patients underwent coronarography and catheterization of the coronary sinus. Blood samples were obtained from the left ventricle and coronary sinus in 3 points: at rest, peak pacing, 10 min after pacing. All patients with stable angina had positive atrial pacing test (pain and/or ECG deviations and lactate production), in control group similar changes were not observed. However, no statistically significant difference was found in platelet factor (IV) 4 levels between the groups and following pacing; the level of platelet factor IV was near 90 ng/ml. It is concluded that patients with stable angina during pacing-induced ischemia had no significant platelet activation, which may provoke thrombotic events.
AuthorsN A Pavlov, E V Pomerantsev, V P Masenko, T I Kupriianenko
JournalBiulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR (Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR) Vol. 12 Issue 2 Pg. 69-71 ( 1989) ISSN: 0201-7369 [Print] USSR
Vernacular TitleSoderzhanie 4-go faktora trombotsitov v krovi na fone indutsirovannoń≠ ishemii miokarda u bol'nykh stabil'noń≠ stenokardień≠.
PMID2604890 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Platelet Factor 4
Topics
  • Adult
  • Angina Pectoris (blood, complications)
  • Coronary Disease (blood, etiology)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurocirculatory Asthenia (blood)
  • Osteochondritis (blood)
  • Platelet Activation (physiology)
  • Platelet Factor 4 (analysis)
  • Spondylitis (blood)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: