Abstract | BACKGROUND: METHODS: Twenty four rats were randomly divided into three groups (n=8). Group 1: the laparotomy group, group 2: ovarian torsion group, and group 3: intervention group administered proanthocyanidinin of 50 mg/kg before bilateral ovarian ischemia and reperfusion. Histologic examination and scoring was done at the end of the experiment. Statistical analyses were performed using the SPSS v. 19. RESULTS: Ovarian histopathologic findings of all three groups were significantly different in terms of hemorrhage (p<0.001), edema (p=0.001) and vascular dilatation (p< 0.001). Pathologic changes induced by I/R were reduced in ovaries of rats administered proanthocyanidin, in particular, hemorrhage, edema and vascular dilatation. CONCLUSION:
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Authors | Şule Yıldırım, Naci Topaloğlu, Mustafa Tekin, Adem Küçük, Havva Erdem, Mesut Erbaş, Ahmet Yıldırım |
Journal | Medical journal of the Islamic Republic of Iran
(Med J Islam Repub Iran)
Vol. 29
Pg. 185
( 2015)
ISSN: 1016-1430 [Print] Iran |
PMID | 26034738
(Publication Type: Journal Article)
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