Single center experience of five diffuse panbronchiolitis patients clinically presenting as severe asthma.

Abstract

Diffuse panbronchiolitis (DPB) is a bronchiolitis affecting the whole lung fields which can be treated by macrolide. Especially East Asian patients are more susceptible to diffuse panbronchiolitis. As asthma and DPB both can cause airway obstruction, differential diagnosis is important for the 2 diseases. Here we report 5 patients with DPB clinically presenting as severe asthma in Korea, who were well treated by macrolide. Among the 5 patients, 2 could stop their asthma inhalers and the other 3 could reduce asthma medications after diagnosis and treatment of DPB. In conclusion, considering DPB as differential diagnosis for asthmatics in Asian ethnic groups is important.

• Authors: Kyung Hee Park, Hye Jung Park, Jae-Hyun Lee, Jung-Won Park
• Journal: Journal of Korean medical science (J Korean Med Sci) Vol. 30 Issue 6 Pg. 823-8 (Jun 2015) ISSN: 1598-6357 [Electronic] Korea (South)
• PMID: 26028938 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Asthmatic Agents
• Macrolides

Topics

• Adult
• Aged
• Anti-Asthmatic Agents (therapeutic use)
• Asthma (diagnosis, drug therapy)
• Bronchiolitis (diagnosis, drug therapy)
• Diagnosis, Differential
• Female
• Haemophilus Infections (diagnosis, drug therapy)
• Humans
• Macrolides (administration & dosage)
• Male
• Middle Aged
• Severity of Illness Index
• Treatment Outcome