Abstract |
Primary hepatic angiosarcoma (PHA) is a rare malignancy that carries a poor prognosis. Of 1500 patients who underwent hepatectomy for primary hepatic tumors between 1994 and 2013 at our center, two patients were pathologically diagnosed with PHA. Clinical characteristics, treatment modalities, and outcomes of the two patients were collected and analyzed. Both patients underwent hepatectomy and had a postoperative survival time of 8 and 16 mo, respectively. A search of PubMed yielded eight references reporting 35 cases of PHA published between 2004 and 2013. On the basis of the presented cases and review of the literature, we endorse complete surgical resection as the mainstay definitive treatment of PHA, with adjuvant postoperative chemotherapy potentially improving survival. Palliative chemotherapy is an option in advanced hepatic angiosarcoma.
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Authors | Yi-Ping Zhu, Yan-Min Chen, Erik Matro, Ren-Biao Chen, Zhi-Nong Jiang, Yi-Ping Mou, Hong-Jie Hu, Chao-Jie Huang, Guan-Yu Wang |
Journal | World journal of gastroenterology
(World J Gastroenterol)
Vol. 21
Issue 19
Pg. 6088-96
(May 21 2015)
ISSN: 2219-2840 [Electronic] United States |
PMID | 26019478
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
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Topics |
- Biomarkers, Tumor
(analysis)
- Biopsy
- Chemoembolization, Therapeutic
- Chemotherapy, Adjuvant
- Fatal Outcome
- Female
- Hemangiosarcoma
(chemistry, pathology, surgery)
- Hepatectomy
- Humans
- Immunohistochemistry
- Liver Neoplasms
(chemistry, pathology, surgery)
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Time Factors
- Tomography, X-Ray Computed
- Treatment Outcome
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