Abstract |
Therapeutic-ultrasound-triggered shape memory was demonstrated for the first time with a melamine-enhanced poly(vinyl alcohol) (PVA) physical hydrogel. The addition of a small amount of melamine (up to 1.5 wt %) in PVA results in a strong hydrogel due to the multiple H-bonding between the two constituents. A temporary shape of the hydrogel can be obtained by deformation of the hydrogel (∼65 wt % water) at room temperature, followed by fixation of the deformation by freezing/thawing the hydrogel under strain, which induces crystallization of PVA. We show that the ultrasound delivered by a commercially available device designed for the patient's pain relief could trigger the shape recovery process as a result of ultrasound-induced local heating in the hydrogel that melts the crystallized PVA cross-linking. This hydrogel is thus interesting for potential applications because it combines many desirable properties, being mechanically strong, biocompatible, and self-healable and displaying the shape memory capability triggered by a physiological stimulus.
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Authors | Guo Li, Qiang Yan, Hesheng Xia, Yue Zhao |
Journal | ACS applied materials & interfaces
(ACS Appl Mater Interfaces)
Vol. 7
Issue 22
Pg. 12067-73
(Jun 10 2015)
ISSN: 1944-8252 [Electronic] United States |
PMID | 25985115
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biocompatible Materials
- Triazines
- Water
- Hydrogel, Polyethylene Glycol Dimethacrylate
- Polyvinyl Alcohol
- melamine
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Topics |
- Biocompatible Materials
(chemistry)
- Crystallization
- Humans
- Hydrogel, Polyethylene Glycol Dimethacrylate
(chemistry, pharmacology)
- Hydrogen Bonding
- Pain Management
- Polyvinyl Alcohol
(chemistry)
- Triazines
(chemistry, pharmacology)
- Water
(chemistry)
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