14 patients of
cor pulmonale in convalescent stage were studied with Swan-ganze
catheter technique. The pulmonary arterial pressure, cardiac output, arterial blood
gases, transcutaneous
gases tension and hemorrheologic measurement were monitored simultaneously at definite intervals within 24 hours. The results showed that the mean value of the pulmonary arterial pressure (MPAP), arterial
carbon dioxide tension (PaCO2), transcutaneous
carbon dioxide tension (tcPCO2), hematocrit(H), whole blood viscosity (eta b) and plasma viscosity (eta p) were higher at night than those at daytime. While the value of cardiac output (CO), arterial
oxygen tension (PaO2) and transcutaneous
oxygen tension (tcPO2) showed a converse result, most of them showed more predominant at daytime and tended to be lowered at night. The MPAP in some of convalescent patients might decrease to normal, but in the
pulmonary hypertension group [MPAP greater than or equal to 2.66 Kpa (20 mmHg)] the day and night measurements of MPAP, CO, PaO2, PaCO2, tcPO2, tcPCO2 were fluctuate more obviously than in normal group (P less than 0.01). The day and night hemorrheologic measurements such as H, eta b, eta p etc. showed that the blood viscosity increased more significantly at night than at daytime. The cardiac output (CO, CI) seemed to be a little bit lower in some patients especially in those with high pulmonary arterial pressure and at night. These results suggest that the variation of the day and night measurements of hemodynamics, blood gas, hemorrheologic changes have some rule.(ABSTRACT TRUNCATED AT 250 WORDS)