Infantile Hemangioma: Clinical Characteristics and Efficacy of Treatment with the Long-Pulsed 1,064-nm Neodymium-Doped Yttrium Aluminum Garnet Laser in 794 Chinese Patients.

Abstract

OBJECTIVE:

This study aimed to evaluate the clinical characteristics of infantile hemangiomas (IHs) and the safety and efficacy of the long-pulse 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for definitive treatment of IHs in 794 Chinese patients.

METHODS:

Infants with hemangiomas who had received long-pulse 1,064-nm Nd:YAG laser treatment in our department in the last 5 years were recruited. Demographic and clinical characteristics were recorded and outcomes of long-pulse 1,064-nm Nd:YAG laser treatment were assessed. Statistical analyses were performed to identify factors that affected the efficacy of treatment.

RESULTS:

The efficacy of long-pulse 1,064-nm Nd:YAG laser for the treatment of IHs in all patients in our study was 87.57%. Efficacy did not depend on sex or the location of the lesion. Older age and superficial hemangioma were the primary factors contributing to greater efficacy of long-pulse 1,064-nm Nd:YAG laser treatment for IHs. The most common side effects were pigment changes, skin atrophy, and wrinkled redundant skin, which usually resolved spontaneously within 1 to 3 years.

CONCLUSIONS:

Long-pulse 1,064-nm Nd:YAG laser is a safe and efficacious treatment for IHs.

• Authors: Shu-xia Zhong, Yu-chun Tao, Jun-feng Zhou, Yuan-yuan Liu, Lei Yao, Shan-shan Li
• Journal: Pediatric dermatology (Pediatr Dermatol) 2015 Jul-Aug Vol. 32 Issue 4 Pg. 495-500 ISSN: 1525-1470 [Electronic] United States
• PMID: 25950113 (Publication Type: Journal Article)
• Copyright: © 2015 Wiley Periodicals, Inc.

Topics

• Female
• Hemangioma, Capillary (radiotherapy)
• Humans
• Infant
• Infant, Newborn
• Laser Therapy (methods)
• Lasers, Solid-State
• Male
• Skin Neoplasms (radiotherapy)
• Treatment Outcome