Abstract | PURPOSE: METHODS: RESULTS: Frequency of reoperation due to recurrent vitreous hemorrhage within 4 weeks after surgery was significantly lower (P = 0.033) in IVB group (3.1%, 1/32) than in sham control group (20.6%, 7/34). The number of intraoperative endodiathermy spots (0.63 ± 1.0 vs. 1.3 ± 1.4, P = 0.025) and frequency of postoperative recurrent vitreous hemorrhage (3.1%, 1/32 vs. 23.5%, 8/34, P = 0.017) were significantly lower in IVB group than in sham control group. Vitreous vascular endothelial growth factor concentrations were 1315.3 ± 1153.4 pg/mL in sham control group and 25.0 ± 13.6 pg/mL in IVB group (P < 0.0001). CONCLUSION:
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Authors | Ayumu Manabe, Hiroyuki Shimada, Takayuki Hattori, Hiroyuki Nakashizuka, Mitsuko Yuzawa |
Journal | Retina (Philadelphia, Pa.)
(Retina)
Vol. 35
Issue 9
Pg. 1800-7
(Sep 2015)
ISSN: 1539-2864 [Electronic] United States |
PMID | 25932549
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Angiogenesis Inhibitors
- VEGFA protein, human
- Vascular Endothelial Growth Factor A
- Bevacizumab
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Angiogenesis Inhibitors
(therapeutic use)
- Bevacizumab
(therapeutic use)
- Diabetic Retinopathy
(diagnosis, physiopathology, surgery)
- Double-Blind Method
- Electrocoagulation
- Female
- Fluorescein Angiography
- Follow-Up Studies
- Humans
- Intravitreal Injections
- Male
- Middle Aged
- Premedication
- Prospective Studies
- Retinal Neovascularization
(diagnosis, drug therapy, physiopathology)
- Tomography, Optical Coherence
- Vascular Endothelial Growth Factor A
(antagonists & inhibitors, metabolism)
- Visual Acuity
(physiology)
- Vitrectomy
- Vitreous Body
(metabolism)
- Young Adult
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