Assessment of Tamsulosin 0.2 mg for Symptomatic Bladder Outlet Obstruction Secondary to Benign Prostatic Enlargement: Data from a Korean Multicenter Cross-Sectional Study.

Abstract

AIMS:

To estimate efficacy and treatment satisfaction with tamsulosin 0.2 mg in patients with symptomatic bladder outlet obstruction secondary to benign prostatic enlargement and lower urinary tract symptoms in relation to personal satisfaction.

METHODS:

The study was conducted in 1,260 subjects who were asked to fill in detailed questionnaires designed to evaluate their satisfaction with the treatment and symptom improvement 8 weeks after receiving tamsulosin 0.2 mg.

RESULTS:

After being treated with tamsulosin 0.2 mg for 8 weeks, the International Prostate Symptom Score (IPSS) score improved significantly. Among the 1,260 patients, 813 (64.52%) were satisfied, while 447 (35.48%) were dissatisfied with tamsulosin 0.2 mg. The reasons for patient dissatisfaction were efficacy problems (79.87%) and side effects (4.25%). Treatment satisfaction was affected by age, underlying medical disease and baseline IPSS severity (p = 0.020, 0.0427 and <0.001, respectively), but only age and baseline IPSS were risk factors for dissatisfaction.

CONCLUSIONS:

Tamsulosin 0.2 mg was effective in symptomatic improvement, but a relatively high proportion of patients were dissatisfied with the treatment. Efficacy problems were selected by patients as the main reason for dissatisfaction. It is also significant to note that the degree of satisfaction was related to age and baseline IPSS severity.

• Authors: Hoon Choi, Ji Sung Sim, Jae Young Park, Jae Hyun Bae
• Journal: Urologia internationalis (Urol Int) Vol. 95 Issue 1 Pg. 50-5 ( 2015) ISSN: 1423-0399 [Electronic] Switzerland
• PMID: 25926099 (Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
• Copyright: © 2015 S. Karger AG, Basel.

Chemical References

• Sulfonamides
• Urological Agents
• Tamsulosin

Topics

• Aged
• Aged, 80 and over
• Cross-Sectional Studies
• Humans
• Lower Urinary Tract Symptoms (complications, drug therapy)
• Male
• Middle Aged
• Patient Satisfaction
• Prostatic Hyperplasia (complications, drug therapy)
• Republic of Korea
• Retrospective Studies
• Risk Factors
• Severity of Illness Index
• Sulfonamides (administration & dosage)
• Surveys and Questionnaires
• Tamsulosin
• Treatment Outcome
• Urinary Bladder Neck Obstruction (drug therapy)
• Urological Agents (administration & dosage)