[Insufficient evidence of the effect of the low FODMAP diet on irritable bowel syndrome].

Abstract

The low FODMAP (Fermentable Oligo-, Di- and Monosaccharides and Polyoles) diet (LFD) allegedly reduces symptoms of irritable bowel syndrome (IBS). Eleven studies have examined the effects of LFD on IBS. Most studies reported a symptomatic effect, but methodological weaknesses such as lack of relevant control group and of proper blinding means that a placebo response cannot be excluded. No studies have examined the effect of the important reintroduction phase nor the effects of LFD on IBS patients in primary care. Evidence suggests that intake of high dose FODMAP can induce gastrointestinal symptoms, but the clinical relevance of this is doubtful.

• Authors: Laura Rindom Krogsgaard, Malene Lyngesen, Peter Bytzer
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 177 Issue 18 Pg. 1503-7 (Apr 27 2015) ISSN: 1603-6824 [Electronic] Denmark
• Vernacular Title: Der er utilstrækkelig evidens for effekten af low-FODMAP-diæt ved colon irritabile.
• PMID: 25922242 (Publication Type: Journal Article, Review)

Chemical References

• Disaccharides
• Monosaccharides
• Oligosaccharides
• Polymers
• Sugar Alcohols
• polyol

Topics

• Diet, Carbohydrate-Restricted
• Disaccharides (adverse effects)
• Evidence-Based Medicine
• Fermentation
• Humans
• Irritable Bowel Syndrome (diet therapy)
• Monosaccharides (adverse effects)
• Oligosaccharides (adverse effects)
• Polymers (adverse effects)
• Sugar Alcohols (adverse effects)
• Treatment Outcome