Abstract |
The inflammatory response is a critical component of the immune system that is activated by stimuli such as cytokines, foreign DNA, RNA, or other harmful substances. Krukenberg et al. (2015) identify poly(ADP-ribose) as a new signaling molecule that activates inflammation, thus providing yet another mechanism by which PARPs are involved in cellular stress responses.
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Authors | Florian J Bock, Paul Chang |
Journal | Chemistry & biology
(Chem Biol)
Vol. 22
Issue 4
Pg. 432-433
(Apr 23 2015)
ISSN: 1879-1301 [Electronic] United States |
PMID | 25910238
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Comment)
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Copyright | Copyright © 2015 Elsevier Ltd. All rights reserved. |
Chemical References |
- Poly Adenosine Diphosphate Ribose
- Poly(ADP-ribose) Polymerases
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Topics |
- Animals
- Humans
- Poly Adenosine Diphosphate Ribose
(pharmacology)
- Poly(ADP-ribose) Polymerases
(metabolism)
- Signal Transduction
(drug effects)
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