HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Macrophage activation: on par with LPS.

Abstract
The inflammatory response is a critical component of the immune system that is activated by stimuli such as cytokines, foreign DNA, RNA, or other harmful substances. Krukenberg et al. (2015) identify poly(ADP-ribose) as a new signaling molecule that activates inflammation, thus providing yet another mechanism by which PARPs are involved in cellular stress responses.
AuthorsFlorian J Bock, Paul Chang
JournalChemistry & biology (Chem Biol) Vol. 22 Issue 4 Pg. 432-433 (Apr 23 2015) ISSN: 1879-1301 [Electronic] United States
PMID25910238 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Comment)
CopyrightCopyright © 2015 Elsevier Ltd. All rights reserved.
Chemical References
  • Poly Adenosine Diphosphate Ribose
  • Poly(ADP-ribose) Polymerases
Topics
  • Animals
  • Humans
  • Poly Adenosine Diphosphate Ribose (pharmacology)
  • Poly(ADP-ribose) Polymerases (metabolism)
  • Signal Transduction (drug effects)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: