Abstract | PURPOSE: METHODS: Using a randomized design, 10 healthy male participants (age 23 ± 4 years, [Formula: see text] 56.8 ± 6.5 ml/kg/min) completed 2 h cycling at 60 % [Formula: see text] in states of euhydration (EH) or dehydration (DH) induced by 24 h fluid restriction. Unstimulated saliva samples were collected before, during, immediately post-exercise and each hour for 3 h recovery. RESULTS: Fluid restriction resulted in a 1.5 ± 0.5 % loss of body mass from baseline and a 4.3 ± 0.7 % loss immediately post-exercise. Pre-exercise urine osmolality was higher in DH than EH and overall, saliva flow rate was reduced in DH compared with EH (p < 0.05). Baseline SIgA secretion rates were not different between conditions; however, exercise induced a significant increase in SIgA concentration in DH (161 ± 134 to 309 ± 271 mg/L) which remained elevated throughout 3 h recovery. SLac secretion rates increased from pre- to post-exercise in both conditions which remained elevated in DH only. Overall, SLac concentrations were higher in DH than EH. Pre-exercise SLys concentrations were lower in DH compared with EH (1.6 ± 2.0 vs. 5.5 ± 6.7 mg/L). Post-exercise SLys concentrations remained elevated in DH but returned to pre-exercise levels by 1 h post-exercise in EH. CONCLUSIONS: Exercise in DH caused a reduction in saliva flow rate yet induced greater secretion rates of SLac and higher concentrations of SIgA and SLys. Thus, DH does not impair saliva AMP responses to endurance exercise.
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Authors | Sophie C Killer, Ida S Svendsen, Michael Gleeson |
Journal | European journal of applied physiology
(Eur J Appl Physiol)
Vol. 115
Issue 9
Pg. 1887-95
(Sep 2015)
ISSN: 1439-6327 [Electronic] Germany |
PMID | 25893563
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Salivary Proteins and Peptides
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Topics |
- Bicycling
- Dehydration
(immunology)
- Exercise
- Humans
- Male
- Physical Endurance
(immunology)
- Saliva
(immunology)
- Salivary Glands
(immunology)
- Salivary Proteins and Peptides
(immunology)
- Young Adult
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