Abstract | PURPOSE OF REVIEW: RECENT FINDINGS: Recent studies have shed light on the possible mechanisms of response to dietary intervention. Epidemiological and rodent model studies over the last year have supplied us with several dietary candidates for an effect of diet on inflammation and disease pathogenesis. Others have shed insight into the effect of diet on dysbiosis and the microbiota. An elimination diet based on some of these candidates has shown clinical efficacy, and bridged the knowledge obtained from rodent models to a human intervention. SUMMARY: These studies may allow better understanding of the pathogenesis of IBD and provide new tools to treat these difficult diseases. Elimination diets based on the identification of deleterious dietary components may pave the way for an improved control of the disease in the future. VIDEO ABSTRACT: http://links.lww.com/COG/ A10.
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Authors | Chen Sarbagili-Shabat, Rotem Sigall-Boneh, Arie Levine |
Journal | Current opinion in gastroenterology
(Curr Opin Gastroenterol)
Vol. 31
Issue 4
Pg. 303-8
(Jul 2015)
ISSN: 1531-7056 [Electronic] United States |
PMID | 25887458
(Publication Type: Journal Article, Review)
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Topics |
- Animals
- Diet
(adverse effects)
- Disease Models, Animal
- Enteral Nutrition
(methods)
- Gastrointestinal Microbiome
- Humans
- Inflammatory Bowel Diseases
(epidemiology, etiology, microbiology, therapy)
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