Abstract | BACKGROUND: METHODS:
Oryeongsan was mixed traditional herbal medicine, Alisma orientale Juz, Polyporus umbellatus Fries, Atractylodes macrocephala Koidez, Poria cocos Wolf and Cinnamomum Cassia Presl (5:3:3:1). Renoprotective role in diabetic nephropathy of Oryeongsan was evaluated by [(3)H]- thymidine incorporation, Western blot, RT-qPCR and immunofluorescence microscopy assay. RESULTS: CONCLUSION:
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Authors | Jung Joo Yoon, Yun Jung Lee, So Min Lee, Dae Gill Kang, Ho Sub Lee |
Journal | BMC complementary and alternative medicine
(BMC Complement Altern Med)
Vol. 15
Pg. 30
(Feb 22 2015)
ISSN: 1472-6882 [Electronic] England |
PMID | 25880429
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Chemokine CCL2
- NF-kappa B
- Plant Extracts
- Smad Proteins
- TIMP2 protein, human
- Transforming Growth Factor beta
- wulingsan
- Intercellular Adhesion Molecule-1
- Tissue Inhibitor of Metalloproteinase-2
- Matrix Metalloproteinase 2
- MMP14 protein, human
- Matrix Metalloproteinase 14
- Glucose
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Topics |
- Animals
- Chemokine CCL2
(metabolism)
- Diabetic Nephropathies
(chemically induced, drug therapy, metabolism)
- Fibrosis
- Glomerular Mesangium
(drug effects, pathology)
- Glucose
(administration & dosage, adverse effects, metabolism)
- Inflammation
(drug therapy, metabolism)
- Intercellular Adhesion Molecule-1
(metabolism)
- Magnoliopsida
- Matrix Metalloproteinase 14
(metabolism)
- Matrix Metalloproteinase 2
(metabolism)
- Mesangial Cells
(drug effects, pathology)
- NF-kappa B
(metabolism)
- Phytotherapy
- Plant Extracts
(pharmacology, therapeutic use)
- Polyporaceae
- Rats
- Signal Transduction
(drug effects)
- Smad Proteins
(metabolism)
- Tissue Inhibitor of Metalloproteinase-2
(metabolism)
- Transforming Growth Factor beta
(metabolism)
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