Abstract | BACKGROUND: AIM: RESULTS: There was a highly significant increase in the level of salivary copper in oral submucous fibrosis patients when compared to controls (P = 0.001). Salivary copper levels were also elevated in oral leukoplakia and oral cancer patients (P = 0.01). There was a significant decrease in the salivary zinc levels in all three study groups when compared to controls (P = 0.001). A highly significant reduction in salivary iron levels was noticed oral submucous fibrosis group. The copper to zinc ratio significantly increased in all the study groups when compared to controls. CONCLUSION:
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Authors | Shishir Ram Shetty, Subhas Babu, Suchetha Kumari, Pushparaja Shetty, Shruthi Hegde, Arvind Karikal |
Journal | Journal of cancer research and therapeutics
(J Cancer Res Ther)
2015 Jan-Mar
Vol. 11
Issue 1
Pg. 146-9
ISSN: 1998-4138 [Electronic] India |
PMID | 25879353
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers
- Trace Elements
- Copper
- Iron
- Zinc
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Topics |
- Biomarkers
- Case-Control Studies
- Copper
- Cross-Sectional Studies
- Humans
- Iron
- Leukoplakia, Oral
(etiology, metabolism, pathology)
- Mouth Neoplasms
(etiology, metabolism, pathology)
- Precancerous Conditions
(etiology, metabolism, pathology)
- Saliva
(chemistry, metabolism)
- Trace Elements
(chemistry, metabolism)
- Zinc
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