Human fascioliasis: a re-emerging disease in upper Egypt.

Abstract

In recent years, the number of humans infected with Fasciola has risen rapidly. Diagnosis is based mainly on detection of eggs in stool analysis. The rate of infection in Egypt is unknown. In this retrospective study, we describe 23 cases of hepatic fascioliasis, and only 2 of these cases showed eggs in stools. The symptoms of infection, such as pyrexia of unknown origin, epigastric pain, and abdominal distension, were suggestive. Imaging techniques, including abdominal ultrasonography and computed tomography, were very helpful in detecting hepatic changes. An indirect hemagglutination assay proved to be of value for diagnosis. Treatment using a 2-day triclabendazole regimen cured the infection and signs of hepatic involvement disappeared. Combining both imaging techniques and laboratory tests is essential for diagnosis of fascioliasis in the early stage.

• Authors: Mohamed A Mekky, Mohammed Tolba, Mohamed O Abdel-Malek, Wael A Abbas, Mohamed Zidan
• Journal: The American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 93 Issue 1 Pg. 76-9 (Jul 2015) ISSN: 1476-1645 [Electronic] United States
• PMID: 25870421 (Publication Type: Journal Article)
• Copyright: © The American Society of Tropical Medicine and Hygiene.

Chemical References

• Anthelmintics
• Benzimidazoles
• Triclabendazole

Topics

• Adolescent
• Adult
• Anthelmintics (therapeutic use)
• Benzimidazoles (therapeutic use)
• Child
• Child, Preschool
• Cholangiopancreatography, Endoscopic Retrograde
• Egypt
• Fascioliasis (complications, diagnosis, drug therapy)
• Feces (parasitology)
• Female
• Fever (etiology)
• Hemagglutination Tests
• Humans
• Jaundice (etiology)
• Liver (diagnostic imaging)
• Male
• Parasite Egg Count
• Retrospective Studies
• Tomography, X-Ray Computed
• Triclabendazole
• Ultrasonography
• Young Adult