Personalized and precision orthodontic therapy.

Abstract

OBJECTIVE:

To bring together orthodontic stakeholders from academics, industry, and private practice for a series of thematically focused workshops to explore and develop the transfer of novel approaches into clinical orthodontic practice.

SETTING AND SAMPLE POPULATION:

Twenty-seven invited speakers, eight poster presenters, and participants of the Consortium for Orthodontic Advances in Science and Technology (COAST) 2014 Innovators' Workshop at the Eaglewood Resort and Spa, Itasca, Illinois, September 11-14, 2014.

MATERIAL AND METHODS:

Five themed sessions involving between 4-7 presentations followed by panel discussions were organized. The aims of the discussion sessions were to highlight important findings and consider the strength of evidence for these, indicate next steps and needed research or technological developments to move forward, and to weigh the expected benefits from these findings and steps to implement in clinical practice.

RESULTS:

Among important areas for attention identified were need for multiscale and multispecies modeling and experimentation for interspecies translation of results; large-scale collaborative efforts within the profession to address the need for adequate sample sizes for future genetic studies of complex traits such as malocclusion; a consortium approach to improve new technologies such as intra-oral scanning and 3D imaging by establishing standards; and harnessing the growing body of knowledge about bone biology for application in orthodontics.

CONCLUSIONS:

With increased awareness of the potential of current and emerging technologies, translation of personalized and precision approaches in the field of orthodontics holds ever-increasing promise.

• Authors: L R Iwasaki, D A Covell Jr, S A Frazier-Bowers, S Kapila, S S Huja, J C Nickel
• Journal: Orthodontics & craniofacial research (Orthod Craniofac Res) Vol. 18 Suppl 1 Pg. 1-7 (Apr 2015) ISSN: 1601-6343 [Electronic] England
• PMID: 25865528 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Topics

• Biomechanical Phenomena
• Computer Simulation
• Congresses as Topic
• Dental Research
• Diagnostic Imaging
• Diffusion of Innovation
• Genome, Human
• Humans
• Orthodontics, Corrective
• Precision Medicine
• Technology Transfer
• Technology, Dental
• Tissue Engineering