[Clinical guideline for management of patients with low risk differentiated thyroid carcinoma].

Abstract

Incidence of thyroid cancer is increasing in Spain and worldwide. Overall thyroid cancer survival is very high, and stratification systems to reliably identify patients with worse prognosis have been developed. However, marked differences exist between the different specialists in clinical management of low-risk patients with thyroid carcinoma. Almost half of all papillary thyroid carcinomas are microcarcinomas, and 90% are tumors < 2 cm that have a particularly good prognosis. However, they are usually treated more aggressively than needed, despite the lack of adequate scientific support. Surgery remains the gold standard treatment for these tumors. However, lobectomy may be adequate in most patients, without the need for total thyroidectomy. Similarly, prophylactic lymph node dissection of the central compartment is not required in most cases. This more conservative approach prevents postoperative complications such as hypoparathyroidism or recurrent laryngeal nerve injury. Postoperative radioiodine remnant ablation and strict suppression of serum thyrotropin, although effective for the more aggressive forms of thyroid cancer, have not been shown to be beneficial for the treatment of low risk patients, and may impair their quality of life. This guideline provides recommendations from the task force on thyroid cancer of the Spanish Society of Endocrinology and Nutrition for adequate management of patients with low-risk thyroid cancer.

• Authors: Juan José Díez, Amelia Oleaga, Cristina Álvarez-Escolá, Tomás Martín, Juan Carlos Galofré, en representación del Grupo de Trabajo de Cáncer de Tiroides de la Sociedad Española de Endocrinología y Nutrición
• Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion (Endocrinol Nutr) 2015 Jun-Jul Vol. 62 Issue 6 Pg. e57-72 ISSN: 1579-2021 [Electronic] Spain
• Vernacular Title: Guía clínica para el manejo de pacientes con carcinoma diferenciado de tiroides de bajo riesgo.
• PMID: 25857691 (Publication Type: Journal Article)
• Copyright: Copyright © 2015 SEEN. Published by Elsevier España, S.L.U. All rights reserved.

Topics

• Humans
• Practice Guidelines as Topic
• Risk Assessment
• Thyroid Neoplasms (pathology, therapy)
• Thyroidectomy (methods, standards)