Hypertrophy of the Left Liver in Patients with Large Tumors in the Right Liver.

Abstract

BACKGROUND:

It has been speculated that, when right-sided major hepatectomy (RSMH) is planned for patients with large tumors in the right liver, it may not lead to a marked decrease in normally functional hepatic mass.

METHODS:

We collected data for patients who had undergone RSMH for tumors more than 8 cm in diameter (n=50) and compared them with control patients who had undergone RSMH for tumors less than 5 cm in diameter (n=21).

RESULTS:

The ratio of the remnant left liver volume to the nontumorous liver volume (left liver ratio) in the patients with large tumors was significantly greater than that in the control group (50.0±12.8% vs. 40.2±8.3%, p=0.002). Left liver ratio was significantly correlated with tumor volume (p<0.001). Preoperative portal vein embolization was performed in only four of the 50 patients with large tumors. None of the patients with large tumors developed postoperative liver failure.

CONCLUSIONS:

Left liver volume in patients with large tumors in the right liver was larger than usual, perhaps reducing the risk of postoperative liver insufficiency after RSMH.

• Authors: Yoshimi Nakayama, Yoichi Ishizaki, Jiro Yoshimoto, Hiroyuki Sugo, Hiroshi Imamura, Seiji Kawasaki
• Journal: World journal of surgery (World J Surg) Vol. 39 Issue 8 Pg. 2031-6 (Aug 2015) ISSN: 1432-2323 [Electronic] United States
• PMID: 25813823 (Publication Type: Clinical Study, Journal Article)

Topics

• Aged
• Bile Duct Neoplasms (diagnostic imaging, pathology, surgery)
• Carcinoma, Hepatocellular (diagnostic imaging, pathology, surgery)
• Case-Control Studies
• Cholangiocarcinoma (diagnostic imaging, pathology, surgery)
• Embolization, Therapeutic (methods)
• Female
• Hepatectomy (methods)
• Humans
• Hypertrophy
• Liver (diagnostic imaging, pathology)
• Liver Failure (epidemiology)
• Liver Neoplasms (diagnostic imaging, pathology, surgery)
• Male
• Middle Aged
• Portal Vein
• Postoperative Complications (epidemiology)
• Preoperative Care
• Tomography, X-Ray Computed
• Tumor Burden