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Sublingual immunotherapy in children and its potential beneficial collateral effect on respiratory tract infections.

Abstract
Although directed to the control of allergic symptoms, a possible effect of sublingual immunotherapy (SLIT) on susceptibility to infections has been hypothesized. Two hundred sixty-five children aged between 3 and 4 years of age affected by allergic rhinitis completed a 6 year prospective case-control study. One hundred forty-three children after 2 years of SLIT reported a lower prevalence of respiratory tract infections when compared to children not undergoing SLIT.
AuthorsFrancesca Occasi, Giovanna De Castro, Anna Maria Zicari, Luciana Indinnimeo, Giancarlo Tancredi, Marzia Duse
JournalCurrent medical research and opinion (Curr Med Res Opin) Vol. 31 Issue 5 Pg. 939-41 (May 2015) ISSN: 1473-4877 [Electronic] England
PMID25753228 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Administration, Sublingual
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Respiratory Tract Infections (immunology, therapy)
  • Rhinitis, Allergic (immunology, therapy)
  • Sublingual Immunotherapy (methods)
  • Treatment Outcome

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