Clinical evaluation of autologous platelet-rich fibrin in the treatment of multiple adjacent gingival recession defects: a 12-month study.

Abstract

Leukocyte- and platelet-rich fibrin (L-PRF) belongs to a new generation of platelet concentrates. There are limited numbers of studies focused on the use of L-PRF in gingival recession defects. This study evaluated the safety and effectiveness of using L-PRF membranes as a substitute for free connective tissue grafts (CTGs) as a treatment method for gingival recession defects. A total of 44 Miller Class I/II gingival recessions that were bilateral, adjacent, and greater than 3 mm in size were selected. Each recession site was randomly assigned to the test group (L-PRF) or the control group (CTG). After 12 months, root coverage was 76.63% and 77.36% in the L-PRF and CTG groups, respectively. It is suggested that L-PRF membrane may be an alternative graft material for treating multiple adjacent recessions greater than 3 mm in size without a requirement for additional surgery.

• Authors: Mustafa Tunalι, Hakan Özdemir, Taner Arabacι, Bahadir Gürbüzer, Levent Pikdöken, Erhan Firatli
• Journal: The International journal of periodontics & restorative dentistry (Int J Periodontics Restorative Dent) Vol. 35 Issue 1 Pg. 105-14 ( 2015) ISSN: 1945-3388 [Electronic] United States
• PMID: 25734713 (Publication Type: Journal Article)

Chemical References

• Fibrin

Topics

• Blood Platelets (metabolism)
• Fibrin (administration & dosage)
• Gingival Recession (therapy)
• Humans
• Postoperative Care