Abstract |
A 6 1-year-old man who was admitted to our hospital because of obstructive jaundice. He was diagnosed with locally advanced cancer of the pancreatic head on computed tomography. Gemcitabine (1,000 mg/m² on days 8 and 15, every 21 days) + S-1 (6 0 mg/m² on day 1-15, every 21 days) chemotherapy was administered because the tumor had invaded the common hepatic artery and portal vein. The tumor was reduced following 9 months of chemotherapy. Thus, subtotal stomach- preserving pancreaticoduodenectomy (SSPPD)was performed. The histopathological findings indicated no invasion of the cancer into the surrounding tissues. No recurrence has occurred 7 months after surgery. Neoadjuvant chemotherapy is important for effective treatment of locally advanced pancreatic cancer.
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Authors | Makoto Moriyama, Shigeaki Sawada, Koshi Matsui, Isaku Yoshioka, Kazuto Shibuya, Soshi Osawa, Toru Yoshida, Takuya Nagata, Kazuhiro Tsukada |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 41
Issue 12
Pg. 2187-9
(Nov 2014)
ISSN: 0385-0684 [Print] Japan |
PMID | 25731465
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Drug Combinations
- Deoxycytidine
- S 1 (combination)
- Tegafur
- Oxonic Acid
- Gemcitabine
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Topics |
- Adenocarcinoma
(drug therapy, surgery)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Deoxycytidine
(administration & dosage, analogs & derivatives)
- Drug Combinations
- Humans
- Male
- Middle Aged
- Neoadjuvant Therapy
- Oxonic Acid
(administration & dosage)
- Pancreatic Neoplasms
(drug therapy, pathology, surgery)
- Pancreaticoduodenectomy
- Tegafur
(administration & dosage)
- Treatment Outcome
- Gemcitabine
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